Fig. 4: NRF2 is involved in the nuclear accumulation of ACSS2. | npj Science of Food

Fig. 4: NRF2 is involved in the nuclear accumulation of ACSS2.

From: Luteolin protects against alcoholic liver injury by restoring NRF2 stability to suppress ACSS2 nuclear accumulation

Fig. 4: NRF2 is involved in the nuclear accumulation of ACSS2.

A Representative immunofluorescence staining of ACSS2 (green) after H2O2 stimulation in primary hepatocytes, nucleus was stained with DAPI (blue) (n = 4, 5). B Representative immunofluorescence staining of ACSS2 (green) after ethanol stimulation in primary hepatocytes, nucleus was stained with DAPI (blue) (n = 4, 5). C Protein expression of acetyl-Histone H3 in primary hepatocytes (n = 4, 5). D Genes expression of Srebp-1c and Fasn in primary hepatocytes (n = 6–8). E Protein expression of acetyl-Histone H3 in primary hepatocytes (n = 4, 5). F Genes expression of Srebp-1c and Fasn in primary hepatocytes (n = 6–8). Values represent the means ± SD. #p < 0.05 vs. Con group; *p < 0.05 vs. Eth group. Con control group, Eth ethanol group.

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