Fig. 5: Integrated Analysis of Transcriptomics and Metabolomics. | npj Science of Food

Fig. 5: Integrated Analysis of Transcriptomics and Metabolomics.

From: Food-grade Lacticaseibacillus paracasei postbiotics suppress oral Streptococcus mutans biofilm formation and cariogenicity

Fig. 5: Integrated Analysis of Transcriptomics and Metabolomics.

A Correlation heatmap between virulence-associated gene expression and differential metabolite abundance. Note: Circles represent correlation strength, with circle size proportional to the absolute value of Pearson’s correlation coefficient (|r | ). The r value indicates Pearson’s correlation between the expression of virulence factors/QS-related genes and metabolite abundance; positive r (red) denotes positive correlation, negative r (blue) denotes negative correlation. B Connectivity network of strongly correlated gene-metabolite pairs (|r | > 0.8). Nodes (genes, triangles; metabolites, stars) are colored by connectedness. Edges represent correlation strength and sign, using solid (positive) or dashed (negative) lines. * P < 0.05, ** P < 0.01, ***P <0.001.

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