Fig. 4

IGF-I modules. This metabolite network is a relayouted version of the metabolite GGM in Fig. 2a. Edge widths reflect absolute partial correlation values. Each colored region corresponds to an identified IGF-I module. For readability, p-values are given in e-notation (e.g., 1.5e−5=1.5·10−5). Node label prefixes P::, U::, and S:: indicate metabolites measured in plasma, urine, and saliva, respectively