Fig. 6

TDL performance and multifactorial impacts on lipid metabolism. a TDL performance in predicting changes in different lipid classes. b In vitro experiments to identify potential contributions of bacteria to produce the statistically different lipids observed between GF and M8 mice ileum samples. c Hypothetical avenues of E. coli mediated impacts on ileum lipid metabolism. Abbreviations: lipid abbreviations tabulated in Table 2, GEM genome-scale metabolic model, Ctrl control, TCA taurocholic acid, HG high glucose, LG low glucose