Table 1 Mean and coefficient of variation (CV) for cell-cycle properties.

From: A hybrid stochastic model of the budding yeast cell cycle

  

Mother cell

Daughter cell

Hybrid model

Experiment

Hybrid model

Experiment

\({T}_{{\rm{div}}}(\min )\)

mean\(\pm\)SE

87\(\pm\)0.22

87\(\pm\)1 (116)

111\(\pm\)0.36

112\(\pm\)3 (97)

\({T}_{{\rm{G}}1}(\min )\)

18\(\pm\)0.06

16\(\pm\)0.59 (158)

37\(\pm\)0.21

37\(\pm\)2 (202)

\({T}_{{\rm{SG}}2{\rm{M}}}(\min )\)

69\(\pm\)0.20

72\(\pm\)1 (116)

73\(\pm\)0.26

76\(\pm\)2 (97)

\({V}_{{\rm{birth}}}({\rm{fL}})\)

41\(\pm\)0.08

40

27\(\pm\)0.05

28

\({T}_{{\rm{div}}}(\min )\)

CV\(\pm\)SE

0.26\(\pm\)0.0017

0.14\(\pm\)0.01 (116)

0.33\(\pm\)0.0023

0.22\(\pm\)0.02 (97)

\({T}_{{\rm{G}}1}(\min )\)

0.35\(\pm\)0.0024

0.50\(\pm\)0.05 (158)

0.60\(\pm\)0.0041

0.50\(\pm\)0.05 (202)

\({T}_{{\rm{SG}}2{\rm{M}}}(\min )\)

0.30\(\pm\)0.0020

0.17\(\pm\)0.02 (116)

0.36\(\pm\)0.0017

0.2\(\pm\)0.06 (97)

\({V}_{{\rm{birth}}}({\rm{fL}})\)

0.28\(\pm\)0.0014

0.18

0.28\(\pm\)0.0014

0.20

  1. Mean \(\pm\) SE and CV \(\pm\) SE computed from simulation of the hybrid stochastic model are compared with experimental observations reported by Di Talia et al.28. The standard errors of the mean are in the same unit of the corresponding characteristic. The number of experimental observations are reported in parenthesis and the number of simulations used to calculate each quantity is at least \(10,000\). \({T}_{{\rm{div}}}\), \({T}_{{\rm{G1}}}\), \({T}_{{\rm{SG}}2{\rm{M}}}\), and \({V}_{{\rm{birth}}}\) are, respectively, cell-cycle duration or the time between two divisions, time from division to next emergence of bud, time from onset of bud to next division, and volume of the cell at birth.