Fig. 1: Outline of the coarse-grained model.
From: Optimal proteome allocation and the temperature dependence of microbial growth laws
Proteins are divided into four main sectors: metabolic proteins (at mass fraction m, in units g/g prot) which convert substrate (s) into precursors (p), ribosomal proteins (r) which synthetize proteins, chaperones (c) which fold proteins, and house-keeping proteins (q). Within the protein sectors, apart from the chaperones, we distinguish between folded and unfolded proteins, as indicated by the indices f and u, respectively. Solid arrows refer to mass flows and dashed arrows to catalytic (enzymatic) activities.
