Fig. 4: Genotoxicity measured in the Cyt-B version of the MN assay.
From: The in vitro micronucleus assay using imaging flow cytometry and deep learning
The percentage of MNed BN cells by microscopy (clear bars), IDEAS (dotted bars), and Amnis AI (striped bars), as well as cytotoxicity measured by microscopy (black circles), IDEAS (red circles), and Amnis AI (blue circles) are shown following a 3 h exposure and 24 h recovery for: (a) Mitomycin C (MMC), (b) Etoposide and (c) Mannitol. Statistically significant increases in MN frequency compared to solvent controls are indicated by asterisks (*P ≤ 0.001).
