Fig. 3: Clear discrimination between male and female mice.
From: Proteotyping of knockout mouse strains reveals sex- and strain-specific signatures in blood plasma
a PC1 and PC2 projection of PCA analysis on all measured proteins shows two groups that can clearly be mapped to male and female mice. b Volcano plot of all measured proteins annotated with the significant discriminators. Positive values on the x-axis indicates increase in the abundance in the plasma of male mice. c Average ROC curve with cross validation using logistic regression on top discriminators showing C-statistics of 97% for the discrimination between males and females. d Boxplots of selected discriminating proteins between male and female mice (center line, median; box limits, upper and lower quartiles; whiskers, 1.5× interquartile range; points, outliers).
