Fig. 3: Functional analysis of novel UM-related susceptibility genes. | npj Systems Biology and Applications

Fig. 3: Functional analysis of novel UM-related susceptibility genes.

From: iUMRG: multi-layered network-guided propagation modeling for the inference of susceptibility genes and potential drugs against uveal melanoma

Fig. 3

Clustered heatmap of top 20 enriched pathways for novel UM-related risk A lncRNAs and C miRNAs, colored by P-values. Network of enriched pathways are colored by functional classes and nodes that share the same cluster are typically close to each other for novel UM-related risk B lncRNAs, D miRNAs and F mRNAs. E Metascape bar graph for viewing enriched pathways of mRNAs, colored by P-values. UM uveal melanoma, lncRNA long non-coding RNA, miRNAs microRNA, AGE-RAGE advanced glycation end products-receptor of RAGE.

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