Table 1 Comparison of different timepoints of our simulations with single-GC data at an unknown timepoint (datasets (viii) and (ix)).

Dataset viii

Unknown, GCs from the same human lymph node

144

(77–591)

30

(20–41)

21

(4.9–28.7)

0.04

(0.01–0.07)

0.17

(0.09–0.33)

0.63

(0.56–0.71)

Dataset ix

Unknown,

gut-associated GCs from several mice

28

(12–101)

7

(3–12)

28.9

(5.9–53.8)

0.18

(0.05–0.39)

0.24

(0.1–0.45)

0.87

(0.68–0.96)

Simulations

0

0

(0–0)

0

(0–0)

–

–

–

–

Simulations

50

96

(86–114)

54

(45–62)

56

(49–63)

0.20

(0.18–0.22)

0.03

(0.02–0.04)

0.9

(0.88–0.90)

Simulations

100

180

(150–198)

80

(73–89)

44

(41–53)

0.22

(0.19–0.23)

0.03

(0.02–0.05)

0.93

(0.91–0.94)

Simulations

150

128

(100–153)

33

(23–42)

26

(19–30)

0.05

(0.02–0.07)

0.19

(0.09–0.27)

0.74

(0.62–0.79)

Simulations

200

59

(43–64)

18

(12–26)

35

(27–41)

0.04

(0.02–0.08)

0.33

(0.15–0.62)

0.59

(0.43–0.71)

Simulations

250

32

(25–41)

15

(11–24)

51

(34–70)

0.06

(0.02–0.12)

0.39

(0.20–0.82)

0.58

(0.27–0.77)

Simulations

300

23

(18–31)

12

(8–19)

56

(34–73)

0.07

(0.04–0.15)

0.39

(0.19–0.88)

0.58

(0.20–0.80)

Simulations

350

17

(15–25)

11

(6–17)

67

(35–82)

0.09

(0.06–0.17)

0.38

(0.19–0.92)

0.57

(0.16–0.80)

Simulations

400

15

(13–21)

11

(4–15)

71

(31–100)

0.11

(0.06–0.2)

0.40

(0.19–0.94)

0.59

(0.13–0.81)

Simulations

450

13

(10–19)

9

(3–16)

75

(30–100)

0.13

(0.07–0.22)

0.46

(0.17–0.96)

0.59

(0.09–0.85)

Simulations

504

11

(4–18)

9

(2–15)

78

(50–93)

0.13

(0.07–0.25)

0.47

(0.15–0.98)

0.60

(0.07–0.85)