Table 2 Comparison and percentage of clones in patient 1 before and after HSCT according to SNVs in PTPN11, SETBP1, and TP53 genes.

From: Potential value of high-throughput single-cell DNA sequencing of Juvenile myelomonocytic leukemia: report of two cases

Clone

Donor

sAML

Patient’s WT clone

PTPN11:chr12:112888165:G/T

WT

Het

WT

TP53:chr17:7579472:G/C

Het

Hom

Hom

SETBP1:chr18:42531907:G/A

WT

Het

WT

% of cells

 Before HSCT

0.0

90.5%

9.5%

 After HSCT

77.2%

12.8%

10.0%

  1. HSCT hematopoietic stem cell transplantation, sAML secondary acute myeloid leukemia, WT wild type.
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