Fig. 4: Metabolic flux map of central carbon metabolism for Synechocystis sp. PCC 6803.

Synechocystis was simulated to grow under autotrophic conditions, with biomass set as objective. Reaction rates (mmol/gDW/h) were predicted using pFBA⁶⁹. Note that, the colors associated with the fluxes are relative to the other reactions rates presented in the map. Irreversible reactions are indicated by one-headed arrows; reversible reactions are indicated by two-headed arrows. For reaction directionality, refer to the data availability section. For metabolic flux maps of central carbon metabolism for biomass simulated to grow mixotrophic conditions, and other objectives simulated to grow under auto- and mixotrophic conditions, refer to Supplementary Figs. 1–9. The map was generated with Escher web-tool⁷². Metabolic reactions and metabolites are indicated by their BiGG identifier⁷³. TCA tricarboxylic acid, GABA branched-chain amino acids γ-aminobutyrate, CBB Calvin–Benson–Bassham, ED Entner–Doudoroff, EMP Embden-Meyerhof-Parnas, PPP pentose phosphate pathway.