Fig. 2: In silico simulation of NFkB KO in the RA M1 macrophage model. | npj Systems Biology and Applications

Fig. 2: In silico simulation of NFkB KO in the RA M1 macrophage model.

From: Large-scale computational modelling of the M1 and M2 synovial macrophages in rheumatoid arthritis

Fig. 2: In silico simulation of NFkB KO in the RA M1 macrophage model.

a Simulation with NFkB active in the model. The Apoptosis phenotype gets inhibited and the Proliferation phenotype gets activated in the presence of NFkB. b Simulation with NFkB inactive in the model. The Apoptosis phenotype gets activated and the Proliferation phenotype gets inhibited in the absence of NFkB.

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