Fig. 3: In silico simulation of GSK3B KO in the RA M2 macrophage model. | npj Systems Biology and Applications

Fig. 3: In silico simulation of GSK3B KO in the RA M2 macrophage model.

From: Large-scale computational modelling of the M1 and M2 synovial macrophages in rheumatoid arthritis

Fig. 3: In silico simulation of GSK3B KO in the RA M2 macrophage model.

a Simulation with GSK3B active in the model. The Apoptosis phenotype gets activated and the Proliferation phenotype gets inhibited in the presence of GSK3B. b Simulation with GSK3B inactive in the model. The Apoptosis phenotype gets inhibited and the Proliferation phenotype gets activated in the absence of GSK3B.

Back to article page