Fig. 12: Validation of simulation results.
From: Radiopharmaceutical transport in solid tumors via a 3-dimensional image-based spatiotemporal model
a A spatial interstitial fluid velocity in tumor and normal tissue (IFV). The red arrows at the tumor’s perimeter indicate that interstitial fluid is directed toward normal tissue from the tumor’s periphery. b IFV in five cross-sections of tumor 1 and normal tissue. c Three-dimensional surface visualization of IFV in tumor 1. d There is a spatial interstitial fluid pressure (IFP). e IFP in five cross-sections of tumor 1 and normal tissue. f Three-dimensional surface visualization of IFP in tumor 1. g Between the present model and the Kletting model10, there is a 13.5% difference in the area under the curve of the amount of labeled PSMA (AUC).
