Fig. 2: Kinase-substrate interaction statistics in the KiNet dataset. | npj Systems Biology and Applications

Fig. 2: Kinase-substrate interaction statistics in the KiNet dataset.

From: A web portal for exploring kinase-substrate interactions

Fig. 2: Kinase-substrate interaction statistics in the KiNet dataset.

KiNet aggregated a dataset of 8365 kinase-substrate interactions from the PhosphoSitePlus, EPSD and iPTMNet databases. a Breakdown of interactions by data sources. The three sources overlapped, but also contributed unique interactions to the KiNet dataset. b Breakdown of data by interaction types. The majority of the interactions include interactions between kinases and non-kinases (n = 7124), but a substantial number of interactions either involved two different kinases (n = 1016), or were autophosphorylations (n = 229).

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