Fig. 6: Interactions between biodomains identified by Integrated Hessians analysis on a multi-modal model trained on samples with complete multi-omics. | npj Systems Biology and Applications

Fig. 6: Interactions between biodomains identified by Integrated Hessians analysis on a multi-modal model trained on samples with complete multi-omics.

From: Effective integration of multi-omics with prior knowledge to identify biomarkers via explainable graph neural networks

Fig. 6

The nodes represent biodomains, and the edges represent interactions, with the edge annotations being the rank of the interaction. The biodomain names based on the 3-letter abbreviations are: apoptosis (apo), lipid metabolism (lip), synapse (syn), endolysosome (end), metal binding (met), cell cycle (cel), mitochondrial metabolism (mit), myelination (mye), vasculature (vas), proteostasis (pro) and APP metabolism (app). The figure was rendered using functions from Matplotlib in Python.

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