Fig. 3: Cohort calibration results. | npj Systems Biology and Applications

Fig. 3: Cohort calibration results.

From: Personalizing neoadjuvant chemotherapy regimens for triple-negative breast cancer using a biology-based digital twin

Fig. 3: Cohort calibration results.

A, B Provides correlations of the measured versus simulated cells and volume for the calibrated V2 time point across all patients. Despite the inclusion of uncertainty from the Bayesian inference, a high mean correlation is achieved for the cohort for the calibration (CCC = 0.99 for Ī”TTC, CCC = 0.99 for Ī”TTV). When predicting the Ī”TTC and Ī”TTV (C, D), the mean correlation decreases to CCC = 0.96 and CCC = 0.89, respectively.

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