Fig. 2 | npj Vaccines

Fig. 2

From: Protein nanovaccine confers robust immunity against Toxoplasma

Fig. 2

CD8-SAPNs elicit restricted CD8+ T and CD4+ T cell peptide-specific immune response. ELISpot showing IFN-γ spot formation. Mouse splenocytes from Empty-SAPN, CD8-SAPN, and CD8-SAPN + GLA-SE were tested using GRA6 peptide (GRA6164–172) or PADRE. GLA designates GLA-SE in this figure. All peptides elicited IFN-γ (p < 0.05) compared to unstimulated cultures. Pooled peptides25 appeared additive. The greatest effect occurred with the polypeptide as also occurred in earlier studies.25 *p < 0.05

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