Fig. 3 | npj Vaccines

Fig. 3

From: LepVax, a defined subunit vaccine that provides effective pre-exposure and post-exposure prophylaxis of M. leprae infection

Fig. 3

Immunization with LepVax delays M. leprae-induced motor nerve damage. Armadillos were monitored for compound muscle action potential (cMAP) and motor nerve conduction velocity (NCV) at monthly intervals following infection and immunization. In a, the first month at which each animal first showed an abnormal nerve conduction was recorded and in b the time at which three consecutive abnormal readings were obtained for each particular animal is noted. The cumulative percent for each group is shown, and data shown are from one of two similar experiments. In c, CMAP measurements from 24 months after infection are shown. Each point depicts the data from a single armadillo, while the box and vertical bars show the mean and s.e.m, respectively. *p-value < 0.05 versus unimmunized, infected control animals

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