Fig. 1 | npj Vaccines

Fig. 1

From: Induction of neutralizing antibody response against koala retrovirus (KoRV) and reduction in viral load in koalas following vaccination with recombinant KoRV envelope protein

Fig. 1

Schematics showing KoRV genome and segment of env protein used for vaccination. a Representative KoRV genome showing coding regions. b Schematic showing segment of env protein used for vaccination, epitope mapping analysis, and membrane proximal external region (MPER) peptide synthesis. rEnv: recombinant envelope protein used for vaccination. The numbers shown represent corresponding amino acid number (GenBank: AF151794). c Layout of the transmembrane subunit of KoRV envelope protein showing important regions. The numbers represent 15mer amino acids peptides overlapping by 12 amino acids. FP fusion peptide, HR1 heptad repeat 1, IS immunosuppressive domain, HR2 heptad repeat 2, MP membrane proximal external region, TM transmembrane region, CP cytoplasmic tail, R-P R-peptide

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