Table 2 Immunoglobulin isotypes in the blood of vaccinated AB6 and WT B6 mice.

From: An attenuated Zika virus NS4B protein mutant is a potent inducer of antiviral immune responses

Ig isotype

AB6

WT B6

WT ZIKV

C100S

WT ZIKV

C100S

IgG

2.24 ± 0.17

2.29 ± 0.12

0.41 ± 0.07

0.57 ± 0.05

IgG1

0.31 ± 0.03

0.33 ± 0.03

0.11 ± 0.00

0.11 ± 0.00

IgG2c

2.64 ± 0.18

2.38 ± 0.14

0.18 ± 0.02

0.14 ± 0.00

IgM

0.42 ± 0.02

0.44 ± 0.03

0.39 ± 0.03

0.70 ± 0.05*

  1. Optical density (OD) of immunoglobulin isotypes and subtypes were determined in sera collected from 4 to 5 vaccinated AB6 or vaccinated WT B6 mice at day 28 after the vaccination. Data are presented as means ± SEM and are representative of at least two similar experiments. *P < 0.05 compared with WT ZIKV-immunized mice (unpaired t-test)
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