Table 1 Characteristics of the 4 Primary and 10 Additional MenB Test Strains.
From: Selection of diverse strains to assess broad coverage of the bivalent FHbp meningococcal B vaccine
Strain | FHbp variant | Percentage identity to vaccine component | Strain MEASURE MFIa (±1 SD) | FHbp variant group MEASURE MFI medianb (±1 SD) | Clonal complex | Country of isolation |
|---|---|---|---|---|---|---|
Primary Strains | ||||||
PMB80 | A22 | 88.9 | 3127 (2440, 4007) | 2502 (1952, 3207) | CC41/44 | United States |
PMB2001 | A56 | 98.1 | 5002 (3903, 6410) | 5002c | CC213 | France |
PMB2948 | B24 | 86.2 | 6967 (5436, 8929) | 8457 (6599, 10,839) | CC32 | France |
PMB2707 | B44 | 91.6 | 11,283 (8804, 14,461) | 14,753 (11,511, 18,907) | CC269 | United Kingdom |
Additional Strains | ||||||
PMB3010 | A06 | 96.2 | 3370 (2629, 4319) | 3088 (2410, 3958) | CC461 | United Kingdom |
PMB3040 | A07 | 85.4 | 1379 (1076, 1767) | 1100 (858, 1409) | CC162 | Germany |
PMB824 | A12 | 85.4 | 2540 (1982, 3255) | 2467 (1925, 3161) | CC35 | United States |
PMB1672 | A15 | 85.1 | 2995 (2337, 3838) | 2904 (2266, 3721) | CC103 | France |
PMB1989 | A19 | 88.1 | 1934 (1509, 2479) | 1759 (1372, 2254) | CC8 | United Kingdom |
PMB3175 | A29 | 93.1 | 3839 (2995, 4920) | 5994 (4677, 7682) | CC32 | United States |
PMB1256 | B03 | 90.8 | 3976 (3102, 5096) | 2935 (2290, 3762) | CC41/44 | United Kingdom |
PMB866 | B09 | 88.1 | 2089 (1630, 2677) | 2275 (1775, 2916) | CC269 | United Kingdom |
PMB431 | B15 | 86.5 | 3785 (2953, 4851) | 4822 (3763, 6180) | CC41/44 | United States |
PMB648 | B16 | 86.2 | 2347 (1831, 3008) | 1996 (1557, 2558) | CC41/44 | United Kingdom |
