Table 2 Optimal observed dose of each component for individual readouts with SE formulation.

From: Preclinical optimization of an enterotoxigenic Escherichia coli adjuvanted subunit vaccine using response surface design of experiments

 

CfaEB (µg)

SLA (µg)

dmLT (µg)

Day 21 serum HAI

10

5

0.03

Day 35 serum HAI

10

5

0.03

Day 35 IW HAI

1.7

0.05

0.17

Day 21 serum LT neutralization

0.3

5

1

Day 35 serum LT neutralization

0.3

5

1

Day 35 IW dmLT IgG

0.3

5

1

Day 35 IW CfaEB IgG

1.7

0.05

0.17

Bone marrow dmLT ASCs

10

0.05

1

Bone marrow CfaEB ASCs

10

5

1

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