Fig. 4: Effect of vaccination on the recurrent disease (days 15–63) following intravaginal challenge with HSV-2 MS strain.

Animals were assessed daily for the presence of recurrent lesions. A Cumulative mean recurrent lesion score. B Total mean recurrent lesion score. The number above the bars is the number of animals with any recurrent disease while the bar shows the mean recurrent lesion score. Error bars are the S.D. a P < 0.01 vs No Vaccine mean recurrent lesion score, b P < 0.05 R2 IM animals with recurrent disease.