Fig. 5: Responses to vaccination during pregnancy are similar in humans and mice.
From: Pregnancy has a minimal impact on the acute transcriptional signature to vaccination
Discordance/concordance plots human vs mouse. Each dot corresponds to a single pair of orthologues. Horizontal axes show the log2 fold change in the tested comparison in murine data. Vertical axes show the log2 fold change in the tested comparison in human data. Colours correspond to the discordance/concordance (disco) score. Red colour indicates high concordance between species and blue colour indicates high discordance between species, i.e. genes regulated in opposite directions. a Non-pregnant individuals; b pregnant individuals; c comparison of interactions between pregnancy and vaccination in murine and human data. d Fold change between unvaccinated and vaccinated samples in mouse (X-axis) and human (Y-axis) samples.
