Fig. 2: Consensus changes during JEV vaccine derivation. | npj Vaccines

Fig. 2: Consensus changes during JEV vaccine derivation.

From: Japanese encephalitis virus live attenuated vaccine strains display altered immunogenicity, virulence and genetic diversity

Fig. 2

The complete genomes of SA14, Clone12-1-7, SA14-2-8, SA14-5-3 and SA14-14-2 were compared. Consensus changes that represent a reversion to the parental, WT strain SA14 are bolded. Consensus changes that occur within the protein coding region of the genome are reported as the codon number within the gene. Consensus changes that occur outside the protein coding region are italicized and reported as a nucleotide number. Sequences of SA14, SA14-2-8, SA14-5-3 and SA14-14-2 were generated in house through Illumina sequencing. The sequence for Clone-12-1-7 was accessed from GenBank (AF416457).

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