Table 1 Comparison of SA14-14-2 in this study and twelve previously genomic sequences from Genbank.

From: Japanese encephalitis virus live attenuated vaccine strains display altered immunogenicity, virulence and genetic diversity

GenBank Accession number						AF416457	MH258851	MH258849	MH258853	MH258852	MH258850	KX254416	KX254417	D90195	MK585066	AF315119	JN604986
Nucleotide Position	CDS Position	Polyprotein	Gene	AA protein #	SA14-14-2	SA14-2-1-7	SA14-14-2	SA14-14-2	SA14-14-2	SA14-14-2	SA14-14-2	SA14-14-2	SA14-14-2	SA14-14-2	SA14-14-2	SA14-14-2	SA14-14-2
21	−74	−24	5′UTR	—	—	—
39	−56	−18	5′UTR	—	—
59	−36	−12	5′UTR	—	—						—				-
127	32	11	C	11	N	S
292	197	66	C	66	S
316	221	74	C	74	K	R
375	280	94	C	94	A	T
518	423	141	prM	14	I										*
884	789	263	prM	136	F										*
1017	922	308	E	14	G	R
1061	966	322	E	28	D
1086	991	331	E	37	D										N
1117	1022	341	E	47	S	N	N	N	N	N	N	N	N	N	N	N	N
1217	1122	374	E	80	A
1296	1201	401	E	107	F
1389	1294	432	E	138	K
1503	1408	470	E	176	V
1506	1411	471	E	177	A	T
1512	1417	473	E	179	E	K	K	K	K	K	K	K	K	K	K	K	K
1532	1437	479	E	185	E	*
1769	1674	558	E	264	H
1813	1718	573	E	279	K		M	M	M	M	M			M	M	M
1921	1826	609	E	315	V	A
1977	1882	628	E	334	P
2012	1917	639	E	345	L	*
2143	2048	683	E	389	D										A
2293	2198	733	E	439	R
2317	2222	741	E	447	G											D
2441	2346	782	E	488	G	*
2691	2596	866	NS1	72	R
2843	2748	916	NS1	122	I
3351	3256	1086	NS1	292	S	G
3493	3398	1133	NS1	339	M	R
3516	3421	1141	NS1	347	R
3528	3433	1145	NS1	351	H	D
3530	3435	1145	NS1	351	H	*
3539	3444	1148	NS1	354	K
3599	3504	1168	NS1	374	E
3652	3557	1186	NS1	392	V	A
3677	3582	1194	NS1	400	G
3776	3681	1227	NS2A	18	A
3801	3706	1236	NS2A	27	L
3929	3834	1278	NS2A	69	A									*
4106	4011	1337	NS2A	128	A	*
4250	4155	1385	NS2B	12	G	*
4403	4308	1436	NS2B	63	D	E
4408	4313	1438	NS2B	65	G
4475	4380	1460	NS2B	87	L											F
4782	4687	1563	NS3	59	V
4825	4730	1577	NS3	73	K
4862	4767	1589	NS3	85	F										*
4921	4826	1609	NS3	105	G
4922	4827	1609	NS3	105	G
5230	5135	1712	NS3	208	I	T
5234	5139	1713	NS3	209	I
5311	5216	1739	NS3	235	V	A											A
5634	5539	1847	NS3	343	R									W
5994	5899	1967	NS3	463	G	S
6008	5913	1971	NS3	467	N
6035	5940	1980	NS3	476	G										*
6425	6330	2110	NS3	606	Q
6634	6539	2180	NS4A	57	I									T
6728	6633	2211	NS4A	88	T	*
6904	6809	2270	NS4A	147	V	A
6944	6849	2283	NS4A	160	A	*
7005	6910	2304	NS4A	181	M	V
7121	7026	2342	NS4A	219	A
7193	7098	2366	NS4A	243	T
7227	7132	2378	NS4A	255	V
7295	7200	2400	NS4B	10	G	*	*	*	*	*	*			*	*	*	*
7655	7560	2520	NS4B	130	A									*
7656	7561	2521	NS4B	131	N	D	D	D	D	D	D	D	D	D	D	D	D
7736	7641	2547	NS5	20	S	*
7768	7673	2558	NS5	31	A											G
7809	7714	2572	NS5	45	R											S
7871	7776	2592	NS5	65	L											*
7926	7831	2611	NS5	84	R	C
8067	7972	2658	NS5	131	D	*
8099	8004	2668	NS5	141	D
8261	8166	2722	NS5	195	M											I
8276	8181	2727	NS5	200	R	*										*
8394	8299	2767	NS5	240	L
8832	8737	2913	NS5	386	Y	H
8882	8787	2929	NS5	402	I	*
8891	8796	2932	NS5	405	V
9122	9027	3009	NS5	482	G	*	*	*	*	*	*	*	*	*	*	*	*
9593	9498	3166	NS5	639	H	Q								Q
9688	9593	3198	NS5	671	A	V
9695	9600	3200	NS5	673	K
9818	9723	3241	NS5	714	C
9898	9803	3268	NS5	741	G	D
9917	9822	3274	NS5	747	P												*
9954	9859	3287	NS5	760	A											P
9971	9876	3292	NS5	765	Q											*
9978	9883	3295	NS5	768	L											V
9995	9900	3300	NS5	773	H											*
10046	9951	3317	NS5	790	V
10139	10044	3348	NS5	821	V
10217	10122	3374	NS5	847	R
10428	10333	3445	3’UTR	918	—	—
10551	10456	3486	3’UTR	959	—	—
10574	10479	3493	3’UTR	966	—											—

Nucleotide position, coding sequence (CDS) nucleotide positions, polyprotein amino acid (AA) position, gene and amino acid position within protein are recorded. Nucleotide changes that do not occur within the CDS and therefore do not result in an amino acid change are recorded as (—). Nucleotide changes that are within the CDS but do not result in an amino acid change are recorded as (*). Single letter amino acid residue codes are used below.

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Table 1 Comparison of SA14-14-2 in this study and twelve previously genomic sequences from Genbank.

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