Fig. 4: Biodistribution of in vivo administered flagellins.
From: Deimmunization of flagellin for repeated administration as a vaccine adjuvant
a Biodistribution of intranasally administered FlaB or dFlaB. BALB/c mice were intranasally administered with 100 μg of FNR675-conjugated FlaB or dFlaB. b Biodistribution of FlaB or dFlaB administered by footpad injection. BALB/c mice were administered with 100 μg of FNR675-conjugated FlaB or dFlaB. Six hours after the administration, the cLNs, iLNs, and pLNs were isolated to determine the biodistribution of the FlaB or dFlaB by measuring fluorescence intensity as described in Materials and methods.
