Fig. 2: Selection and diversity in core pneumococcal genes and the selected antigens.
From: Pneumococcal capsule blocks protection by immunization with conserved surface proteins
Top panel: marginal density distribution of πaa (a measure of the average number of coding changes between a pair of sequences from different isolates) showing the position of the selected antigens with red dashed lines, as labeled. Right panel: marginal density distribution of dN/dS (ratio of non-synonymous to synonymous changes). Central panel: scatter plot of average pairwise sequence diversity πaa vs selection strength for all core genes (black) and tested antigens (red).
