Fig. 5: LmexCen−/− immunization promotes generation of T central memory cells in BALB/c mice. | npj Vaccines

Fig. 5: LmexCen−/− immunization promotes generation of T central memory cells in BALB/c mice.

From: Centrin-deficient Leishmania mexicana confers protection against New World cutaneous leishmaniasis

Fig. 5: LmexCen−/− immunization promotes generation of T central memory cells in BALB/c mice.

a Schematic of the vaccination study design for BALB/c mice. b Percentage of CD4+CD44+CD62L+ T cells in the draining lymph nodes of PBS-injected mice and mice immunized with LmexCen−/− parasites at 6 wpi analyzed via flow cytometry. Data show one representative experiment with mean ± SEM, N = 3 for each group. Unpaired two-tailed Student’s t-test was performed to compare statistical significance. A P-value < 0.05 was considered significant. In all panels * represents P ≤ 0.05, ** represents P ≤ 0.01, and *** represents P ≤ 0.001.

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