Fig. 9: LmexCen−/− immunization mediates an enhanced Th1 response in C57BL/6 ears challenged with LmexWT. | npj Vaccines

Fig. 9: LmexCen−/− immunization mediates an enhanced Th1 response in C57BL/6 ears challenged with LmexWT.

From: Centrin-deficient Leishmania mexicana confers protection against New World cutaneous leishmaniasis

Fig. 9: LmexCen−/− immunization mediates an enhanced Th1 response in C57BL/6 ears challenged with LmexWT.

a Percentage of CD4+IFN-γ+ T cells in the ear of vaccinated and control mice at 14 wpc analyzed via flow cytometry. b Percentage of CD4+IL-10+ T cells in the ear of vaccinated and control mice at 14 wpc analyzed via flow cytometry. c Percentage of CD4+IL-4+ T cells in the ear of vaccinated and control mice at 14 wpc analyzed via flow cytometry. Data show one representative experiment out of two independent experiments and show mean ± SEM, N = 5 for each group at each time point. Unpaired two-tailed Student’s t-test was performed to compare statistical significance. A P-value < 0.05 was considered significant. In all panels * represents P ≤ 0.05, ** represents P ≤ 0.01, and *** represents P ≤ 0.001.

Back to article page