Fig. 3: Gcc-foldon and Gcc-Conc elicit higher Gacc-specific Abs than Gcc-NP in MIMIC®. | npj Vaccines

Fig. 3: Gcc-foldon and Gcc-Conc elicit higher Gacc-specific Abs than Gcc-NP in MIMIC®.

From: Immunogenicity and protective efficacy of RSV G central conserved domain vaccine with a prefusion nanoparticle

Fig. 3: Gcc-foldon and Gcc-Conc elicit higher Gacc-specific Abs than Gcc-NP in MIMIC®.

Gacc-binding IgG titers were measured after stimulating cells with Gcc-NP, Gcc-Foldon or Gcc-Conc in MIMIC, and determined using the Antibody Forensics technique with Luminex beads coated with peptide corresponding to the RSV Gcc of strain A2. Each dot represents a response from an individual donor, the lines indicate the geometric means, and the error bars represent 95% confidence intervals. N = 22. All statistical values were performed using Student’s t-test.

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