Table 3 Summary of economic parameters used.

 DSTB diagnosis, per patient

26.52

32

Cost per Xpert test

 DSTB treatment, per episode

185.86

32

Category 1 treatment episode

 Vaccine price, per course

10

Expert opinion

Two doses per course. 5% wastage assumed.

 Freight, per dose

1

Assumed

10% of vaccine price

 Social mobilisation, per dose

0.08

33

 Cold chain (service level), per dose

0.01

34

 Transport(facility-based), per dose

0.04

34

 Transport for outreach services, per dose

0.004

33

 Vaccinator cost, per dose

0.69

35,36

5 minutes of vaccinator time per dose assumed. Vaccinator cost based on the 2019 median annual salary of a professional nurse in South Africa.

 Per diem for outreach service delivery, per dose

1.39

34

Per diems and allowances paid to vaccinators for service delivery during outreach activities. Estimated median value based on previous vaccination campaigns

 Cold chain (service level), per dose

0.01

34

 Transport(facility-based), per dose

0.04

34

 Social mobilisation, per dose

0.08

33

 Vaccinator cost, per dose

0.69

35,36

5 minutes of vaccinator time per dose assumed. Vaccinator cost based on the 2019 median annual salary of a professional nurse in South Africa.

 ART cost per patient year

254

37

 Upper health care opportunity cost threshold for South Africa (USD)

2480

38

 Lower health care opportunity cost threshold for South Africa (USD)

3334

38

 1-times GDP per capita South Africa 2019

6001

39

 3-times GDP per capita South Africa 2019

18,004

39