Table 1 Overview of studies and results.

Primary vaccination series
			No. Obs	No. of Sera	Fold decrease (Omicron)			Median % responders (Omicron)	Median GMT (Parent)
Type of vaccination	Platform	Vaccine	No. Obs	No. of Sera	Q1	Median	Q3	Median % responders (Omicron)	Median GMT (Parent)
Homologous	Inactivated	BBIBP-CorV	4	325	1.9	7.2	11.2	23	67.4
	Inactivated	CoronaVac	4	135	5.4	9.5	14.5	0	32.5
	mRNA	mRNA-1273	14	275	15.8	25.5	42.6	94	1039
	mRNA	Comirnaty	33	777	18.9	23.1	34.7	38	347.9
	Vector	Vaxzevria	6	131	13.3	17.5	25	12	133
		Sputnik V	2	26	7.6	7.6	7.6	44.5	66.5
		Ad26.COV2.S	7	128	3.0	6.2	10.7	8.5	96
Heterologous	Vector + mRNA	Vaxzevria + mRNA-1273	1	11	19.5	19.5	19.5	82	671.4
Heterologous	Vector + mRNA	Vaxzevria + Comirnaty	1	15	24.5	24.5	24.5	80	661.6
Total			72	1823
Booster
Homologous	Inactivated	BBIBP-CorV (3 doses)	4	408	8.6	11.4	15.8	78	361.8
	Inactivated	CoronaVac (3 doses)	2	70	9.7	13.1	16.5	72.5	164.3
	mRNA	mRNA-1273 (3 doses)	7	74	4.2	5.5	15	100	3942
	mRNA	Comirnaty (3 doses)	19	438	4	7.4	13.1	100	1749.5
	Protein subunit	Anhui ZL (3 doses)	3	44	3	9.4	10.6	56	329
	Vector	Sputnik V + Sputnik Light	1	6	7.1	7.1	7.1	100	359.2
	Vector	Ad26.COV2.S (2 doses)	1	20	2.8	2.8	2.8	100	127.6
Heterologous	Inactivated + Protein subunit	BBIBP-CorV + Anhui ZL	2	20	11.8	13.4	14.9	90	1527.5
	Inactivated + mRNA	CoronaVac + Comirnaty	2	85	6.1	6.7	7.3	100	320
	mRNA + mRNA	mRNA-1273 + Comirnaty	1	4	13.1	13.1	13.1	75	984.3
	mRNA + mRNA	Comirnaty + mRNA-1273	1	4	9.8	9.8	9.8	100	1378.6
	mRNA + Vector	Comirnaty + Ad26.COV2.S	2	61	2.9	3.6	4.2	100	2456.3
	Vector + mRNA	Ad26.COV2.S + Comirnaty	1	20	-	-	-	100	1044.9
	Vector + Protein subunit	Vaxzevria + MVC-COV1901	1	73	6.6	6.6	6.6	N/R	404.8
Total			47	1327

Results for each vaccine regimen (primary series and booster), with median fold change against Omicron, IQR, and median GMT against the parent strain (which was chosen to be similar to the vaccine-seed strain). Results could not be extracted; N/R Not Reported. References ^{4,5,6,7,8,9,10,11,12,13,14,15,16,17,18,19,20,21,22,23,24,25,26,27,28,29,30,31,32,33,34,35,36,37,38,39,40,41,42,43,44,45,46,47,48,49,50,51,52,53} were used to collect the source data used in the analysis, which can be found in the Source Data file.

Search