Table 1 Summary of fertility and caesarean section data in main study cohort of Study 1 (EFD).
Indicators | Blank control | Adjuvant control | ZF2001 25 μg/dose | ZF2001 50 μg/dose |
|---|---|---|---|---|
Female mating index | 17/24 (70.8%) | 21/24 (87.5%) | 19/24 (79.2%) | 19/24 (79.2%) |
Pregnancy rate | 16/17 (94.1%) | 21/21 (100%) | 17/19 (89.5%) | 17/19 (89.5%) |
Fertility index | 16/24 (66.7%) | 21/24 (87.5%) | 17/24 (70.8%) | 17/24 (70.8%) |
Weight of uterus and embryo (g) | 77.75 ± 14.20 | 80.27 ± 17.03 | 78.75 ± 21.97 | 84.39 ± 15.90 |
Placenta weight (g) | 0.49 ± 0.05 | 0.51 ± 0.07 | 0.55 ± 0.07* | 0.55 ± 0.08* |
Corpus lutea | 18.25 ± 3.49 | 17.62 ± 3.17 | 16.18 ± 2.43 | 16.88 ± 2.55 |
Implantation sites | 13.88 ± 2.33 | 13.90 ± 3.14 | 14.06 ± 2.75 | 14.76 ± 1.71 |
Live fetuses | 13.44 ± 2.39 | 13.71 ± 3.24 | 13.12 ± 3.87 | 14.00 ± 2.85 |
Live fetuses rate (%) | 96.8 ± 4.7 | 98.5 ± 3.3 | 91.4 ± 17.9 | 94.8 ± 15.9 |
Dead fetuses | 0.00 ± 0.00 | 0.05 ± 0.22 | 0.12 ± 0.33 | 0.06 ± 0.24 |
Dead fetuses rate (%) | 0.0 ± 0.0 | 0.4 ± 1.8 | 0.9 ± 2.6 | 0.3 ± 1.4 |
Resorptions | 0.44 ± 0.63 | 0.14 ± 0.36 | 0.82 ± 1.74 | 0.71 ± 2.20 |
Resorptions rate (%) | 3.2 ± 4.7 | 1.1 ± 2.9 | 7.7 ± 16.4 | 4.9 ± 15.6 |
Preimplantation loss rate (%) | 21.7 ± 17.4 | 19.7 ± 18.5 | 13.1 ± 14.6 | 11.8 ± 9.4 |
Postimplantation loss rate (%) | 3.2 ± 4.7 | 1.5 ± 3.3 | 8.6 ± 17.9 | 5.2 ± 15.9 |
Sex ratio (% male) | 51.5 ± 8.3 | 48.9 ± 15.2 | 49.1 ± 14.3 | 47.9 ± 13.0 |
Fetal body weight (g) | 3.82 ± 0.21 | 3.82 ± 0.25 | 3.68 ± 0.46 | 3.82 ± 0.36 |
Fetal body length (cm) | 3.77 ± 0.08 | 3.78 ± 0.11 | 3.70 ± 0.19 | 3.75 ± 0.12 |
Fetal tail length (cm) | 1.15 ± 0.03 | 1.15 ± 0.04 | 1.14 ± 0.07 | 1.15 ± 0.04 |
