Table 7 Summary of reproductive performance of F1 offspring rats in PPND study.
Indicators | Blank control | ZF2001 25 μg/dose |
|---|---|---|
Total pairs cohabited | 16 | 16 |
Mated females | 16 | 15 |
Pregnant females | 15 | 14 |
Time to mating (days) | 3.3 ± 1.7 | 3.2 ± 0.9 |
Mating index (%) | 100 | 93.8 |
Pregnancy (%) | 93.8 | 93.3 |
Fertility index (%) | 93.8 | 87.5 |
Corpus lutea | 21.2 ± 6.8 | 23.6 ± 5.2 |
Implantation | 16.2 ± 1.9 | 16.3 ± 2.5 |
Live fetuses | 14.8 ± 2.1 | 14.9 ± 2.2 |
Live fetuses (%) | 91.4 ± 9.8 | 91.5 ± 7.8 |
Dead fetuses | 0.0 ± 0.0 | 0.0 ± 0.0 |
Dead fetuses (%) | 0.0 ± 0.0 | 0.0 ± 0.0 |
Resorptions | 1.4 ± 1.7 | 1.4 ± 1.4 |
Resorptions (%) | 8.6 ± 9.8 | 8.5 ± 7.8 |
Preimplantation loss (%) | 19.9 ± 15.1 | 28.4 ± 15.9 |
Postimplantation loss (%) | 8.6 ± 9.8 | 8.5 ± 7.8 |