Table 4 Small-molecule drugs and chemical compounds that regulate gene expression in an opposite manner to BNT162b2.
Compound | Score | Description | Links to hypothalamic-pituitary-ovarian function |
|---|---|---|---|
Droxinostat | −94.51 | HDAC inhibitor | |
Metyrapone | −93.62 | Cytochrome P450 inhibitor | |
Perospirone | −92.07 | Dopamine receptor antagonist | |
Nabumetone | −88.8 | Cyclooxygenase inhibitor | |
Salbutamol | −87.35 | Adrenergic receptor agonist | |
VU-0415374-1 | −86.32 | Glutamate receptor modulator | |
Bromfenac | −83.64 | Cyclooxygenase inhibitor | |
PF-3845 | −82.22 | FAAH inhibitor | |
Hexylresorcinol | −80.48 | Local anesthetic | |
PPT | −80.07 | Estrogen receptor agonist |
