Fig. 1: The gaussian mixture model shows an increasing spread in particle size distributions as the VLPs thermally age.
From: Analyzing atomic force microscopy images of virus-like particles by expectation-maximization

Optimized Gaussian Mixture Model profiles for the single pass AFM images based on VLP area following 2-hours (A), 3-hours (B) and 4-hours (C) of thermal aging. The VLP suspensions were left at room temperature for 2–4 hours prior to placement on a mica surface.