Table 2 Adjusted and unadjusted odds ratios (ORs with 95% CI) of a negative IgG test result after at least two doses of COVID-19 vaccine for individuals in the primary care cohort (Model A)
From: Association between antibody responses post-vaccination and severe COVID-19 outcomes in Scotland
Risk Factors (Reference) | Odds Ratios (95% CI) | |
|---|---|---|
Unadjusted | Adjusted | |
Care Home Resident (No) | ||
Yes | 1.81 (1.07–3.06) | 1.02 (0.55–1.89) |
Shielding (No) | ||
Yes | 2.38 (2.05–2.76) | 1.68 (1.38–2.04) |
Immunosuppressed (No) | ||
Yes | 1.22 (0.99–1.50) | 1.05 (0.83–1.33) |
Severely | 2.66 (2.23–3.17) | 2.25 (1.80–2.83) |
Prior SARs-CoV-2 Infection (No) | ||
Yes | 0.09 (0.06–0.15) | 0.13 (0.08–0.21) |
Number of QCOVID Risk Groups (0) | ||
1 | 1.44 (1.25–1.67) | 1.05 (0.89–1.24) |
2 | 1.93 (1.63–2.29) | 1.07 (0.88–1.31) |
3-4 | 2.99 (2.51–3.57) | 1.38 (1.11–1.72) |
5+ | 4.72 (3.53–6.31) | 1.94 (1.36–2.77) |
BMI (18.5–25) | ||
Unknown | 0.75 (0.63–0.91) | 1.12 (0.90–1.39) |
<18.5 | 0.99 (0.59–1.69) | 0.97 (0.53–1.76) |
25-30 | 1.22 (1.01–1.48) | 1.17 (0.94–1.45) |
30+ | 1.49 (1.24–1.79) | 1.55 (1.27–1.90) |
SIMD (3) | ||
1 | 1.02 (0.85–1.22) | 0.95 (0.78–1.16) |
2 | 1.06 (0.89–1.26) | 1.03 (0.85–1.25) |
4 | 0.95 (0.80–1.13) | 1.04 (0.86–1.26) |
5 | 0.92 (0.76–1.11) | 1.00 (0.81–1.24) |
Unknown | 0.36 (0.11–1.15) | 0.37 (0.11–1.23) |
Sex (Female) | ||
Male | 1.10 (0.98–1.23) | 1.06 (0.93–1.20) |
Vaccine Dose (2 Doses Pfizer or Moderna) | ||
Two doses of ChAdOx1 | 12.38 (10.06–15.24) | 9.90 (7.87–12.45) |
Mixed 3+ doses (including ChAdOx1) | 0.60 (0.40–0.89) | 0.68 (0.41–1.12) |
Mixed 3+ doses (no ChAdOx1) | 0.34 (0.20–0.60) | 0.42 (0.23–0.77) |
