Fig. 3: Antibodies are long-lived with affinity maturation and B-cell memory responses taking place independent on T cells. | npj Vaccines

Fig. 3: Antibodies are long-lived with affinity maturation and B-cell memory responses taking place independent on T cells.

From: T cell independent antibody responses with class switch and memory using peptides anchored on liposomes

Fig. 3

WT BALB/c and athymic nude mice were immunized with 10 µg Lip-OVA58-72 and boosted 14 weeks later. a Specific IgG1, IgG2a, IgG2b and IgG3 antibody responses to the whole OVA were measured at the indicated time points and the results are expressed as mean ± SD (n = 5). b Avidity of the measured antibodies on week 23 after immunization as analyzed by competitive ELISA. The number above the bars indicate the avidity fold increase between weeks 1 and 23.

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