Fig. 8: Immunization with liposomal TI vaccines reduced bacterial infection in mice. | npj Vaccines

Fig. 8: Immunization with liposomal TI vaccines reduced bacterial infection in mice.

From: T cell independent antibody responses with class switch and memory using peptides anchored on liposomes

Fig. 8

BALB/c mice (n = 5) were immunized with a combination of Lip-OVA58-72 and Lip-OVA179-195 (Lip), with OVA protein on alum (Alu) or left untreated. On day 7, all mice were infected with OVA-expressing L monocytogenes. On day 9, the mice were euthanized and the bacterial burden in liver was determined by plating tissue homogenates on agar and calculating CFU. Geometric means are shown and the results were analyzed using Kruskal Wallis tests comparing the two immunized groups to the non-immunized group. Statistical p values are indicated.

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