Fig. 3: Differentially expressed genes (DEGs) identification. | npj Vaccines

Fig. 3: Differentially expressed genes (DEGs) identification.

From: Calcifediol boosts efficacy of ChAdOx1 nCoV-19 vaccine by upregulating genes promoting memory T cell responses

Fig. 3

a Normalization of raw counts by DESeq 2 using Variance Stabilizing Transformation (VST). b Principal Component Analysis (PCA) of calcifediol supplemented (treated) cohorts, where blue bubbles represent baseline, red bubbles represent 3rd month and green bubbles represent 6th month. c Comparisons of the numbers of differentially expressed genes [differentially expressed (DE) features] at various time points. d Venn Diagrams depicting common and unique Upregulated and (e) downregulated differentially expressed genes in the calcifediol supplemented subjects at the 3rd and 6th month.

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