Fig. 6: LVRNA001 was highly immunogenic in cynomolgus macaques.
From: Safety and efficacy assessment of an mRNA rabies vaccine in dogs, rodents, and cynomolgus macaques
Cynomolgus macaques were injected with LVRNA001 at a low dose of 50 μg, a high dose of 150 μg, empty LNP, or Saline on D0, D7, D21, and D35. a Viral neutralization titers from serum samples was detected through FAVN on D3, D7, D21, D35, and D64. n = 10, except for D64 (n = 4). b IFN-γ secreting cells were examined using ELISPOT assay on D39. n = 5. All error bars represent standard deviation. Statistical analysis was performed using an ordinary one-way ANOVA. *p < 0.05.
