Fig. 2: Antigenic heat map of H5-Re11 mutants.
From: A broad-spectrum vaccine candidate against H5 viruses bearing different sub-clade 2.3.4.4 HA genes
The antigenicity of the H5-Re11 variants was determined by quantifying HI titers utilizing a panel of 19 mAbs generated in our laboratory. A 4-fold difference in antigenicity was deemed significant.
