Table 1 Cross-reactive HI antibody titers of mutant viruses with different antisera
From: A broad-spectrum vaccine candidate against H5 viruses bearing different sub-clade 2.3.4.4 HA genes
Virus (H5 numbering) | Serum | Virus titer | ||
|---|---|---|---|---|
H5-Re8 | H5-Re11 | EID50/ml | HA (log2) | |
Re8 | 2048 | 64 | 8.63 | 8 |
Re11 | 256 | 256 | 8.63 | 8 |
Re11_K40R | 256 | 256 | 8.17 | 7 |
Re11_Q115L | 256 | 256 | 8.83 | 8 |
Re11_R120S | 256 | 256 | 8.83 | 8 |
Re11_S123P | 256 | 256 | 8.63 | 8 |
Re11_N124D | 256 | 256 | 8.63 | 8 |
Re11_-126D | 512 | 256 | 8.17 | 8 |
Re11_S129L | 256 | 256 | 8.63 | 8 |
Re11_V140M | 256 | 256 | 8.50 | 7 |
Re11_A141P | 256 | 256 | 9.17 | 8 |
Re11_T151I | 256 | 256 | 8.83 | 8 |
Re11_A156T | 256 | 256 | 9.17 | 8 |
Re11_K169R | 256 | 256 | 9.17 | 7 |
Re11_S183N | 256 | 256 | 8.63 | 8 |
Re11_E185A | 256 | 256 | 9.17 | 8 |
Re11_R234K | 256 | 256 | 9.17 | 8 |
Re11_I257V | 256 | 256 | 8.17 | 8 |
Re11_T259K | 256 | 256 | 8.83 | 8 |
Re11_I269M | 256 | 256 | 8.83 | 8 |
Re11_N273H | 256 | 256 | 8.17 | 8 |
Re11_S320N | 256 | 256 | 8.83 | 8 |
