Table 1 Schematic illustration of vaccines assessed for an increase in adjuvant to antigen ratio

From: A synthetic cyclic peptide for promoting antigen presentation and immune activation

Vaccine Name

Adjuvant

Antigen

VC-13

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VC-16

Adjuvant ratio increased by 2×

VC-17

Adjuvant ratio increased by 4×

VC-18

Adjuvant ratio increased by 8×

PADRE-J8 + CFA

CFA

  1. J8 B cell antigen (QAEDKVKQSREAKKQVEKALKQLEDKVQ); PADRE T helper epitope (AKFVAAWTLKAAA). Positive (PADRE-J8 + CFA) and negative (PBS) controls were used. ‘VC’ represents ‘vaccine candidate’.