Table 2 GAS peptide antigen properties
From: A synthetic cyclic peptide for promoting antigen presentation and immune activation
Peptide Antigen | Peptide Sequence | Sequence Length/% Ratio Hydrophilic Residues | Net Charge at pH 7.0 | Predicted Secondary Structure* | Isoelectric Point |
|---|---|---|---|---|---|
J8 | NH2-QAEDKVKQSREAKKQVEKALKQLEDKVQ-CONH2 | 28/71 | 3 | Alpha helix: 82% Coil: 18% | 10.19 |
NS1 | NH2-RVTTRSQAQDAAGLKEKAD-CONH2 | 19/53 | 2 | Coil: 100% | 10.63 |
88/30 | NH2-DNGKAIYERARERALQELGP-CONH2 | 20/50 | 1 | Alpha helix: 75% Coil: 25% | 9.66 |
GnRH | NH2-EHWSYGLRPG-CONH2 | 10/30 | 1 | Coil: 100% | 9.85 |
PADRE | NH2-AKFVAAWTLKAAA-CONH2 | 13/15 | 3 | Coil: 23% Beta sheet: 77% | Not determined |
Cyclic decapeptide | -AK(alkyne)APGKK(alkyne)APG- | 10/30 | 1 | ** Alpha helix: 2.7% Beta sheet: 26.4% Beta turn: 19.4% Coil: 51.5% | Not determined |
Lipid peptide | NH2-KKSS-C16-C16-CONH2 | 6/66 | 3 | ** Beta sheet: 45.8% Beta turn: 13.5% Coil: 40.7% | Not determined |
