Fig. 1: Alignment of HA nucleotide sequence (nucleotides 1008-1070 of the coding sequence).
From: Influenza A virus in dairy cattle: infection biology and potential mammary gland-targeted vaccines
The peptide sequence corresponding to the cleavage site is shown on the right (blue rectangle highlights the stretch of basic residues upstream of the cleavage site). Alignment was performed using the “emma” and “shoawalign” tools in EMBOSS and manually edited. A few representative sequences from the Eurasian set of H5 sequences (up to year 1996) were retrieved from the Influenza virus resource. Sequences 1 and 9, corresponding to previous HPAIVs in Europe, were included for comparison.
