Fig. 6: Combined fentanyl and heroin vaccine formulation elicits high-titer antibody responses with some cross-reactivity. | npj Vaccines

Fig. 6: Combined fentanyl and heroin vaccine formulation elicits high-titer antibody responses with some cross-reactivity.

From: Two doses of Qβ virus like particle vaccines elicit protective antibodies against heroin and fentanyl

Fig. 6: Combined fentanyl and heroin vaccine formulation elicits high-titer antibody responses with some cross-reactivity.

Endpoint dilution IgG titers (geometric mean titer) against fentanyl (A), morphine (B), naltrexone (C), methadone (D), and buprenorphine (E). Mice (Balb/cJ, n = 12, male and female) were immunized twice with Qβ-fentanyl, Qβ-morphine + Qβ-6-AM, or Qβ-fentanyl + Qβ-morphine + Qβ-6-AM (20 μg or 10 μg doses). Antibody titers were assessed at day 28 (day 7 post-second immunization).

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